Cofactors of wheat-dependent exercise-induced anaphylaxis do not increase highly individual gliadin absorption in healthy volunteers

Table 3 Gliadin levels in serum expressed as areas under the curve (AUC) after each intervention

Proband	Gluten	Gluten + PPI	Gluten + ASA	Gluten + alcohol	Gluten + aerobic exercise	Gluten + anaerobic exercise	Mean (P) (n = 6)¹
Proband	(area under the curve)
P1	55,562	123,910	54,048	48,029	69,791	30,625	63,661^ABCD
P2	12,6888	158,897	83,468	80,954	81,162	85,541	102,818^DEF
P3	12,9994	132,946	99,449	119,755	162,707	158,978	133,971^F
P4	94,900	71,054	74,315	75,912	94,554	117,046	87,964^CDE
P5	65,023	69,845	49,792	44,235	61,865	66,233	59,499^ABC
P6	57,197	29,083	36,223	50,788	55,538	44,863	45,615^AB
P7	55,415	27,179	10,154	22,164	36,063	30,860	30,306^A
P8	37,965	54,002	38,267	22,756	27,404	27,652	34,674^AB
P9	66,551	79,698	50,321	74,795	79,739	81,292	72,066^BCDE
P10	48,213	101,761	93,939	67,814	79,805	129,075	86,768^CDE
P11	89,426	80,983	89,920	124,277	123,449	129,796	106,308^EF
P12	48,217	86,500	99,754	72,879	101,717	129,330	89,733^CDE
Median	61,110	80,340	64,182	70,346	79,772	83,416
Mean (I)²	72,946^A	84,655^A	64,971^A	67,030^A	81,149^A	85,941^A
SEM	8845	11,499	8438	9351	10,705	13,359

Values in italics designate the highest AUC for each proband
ASA acetyl salicylic acid, PPI proton pump inhibitor, SEM, standard error of the mean
¹Mean (P) designates the mean AUC of all six interventions per proband displayed per row. Different superscript capital letters indicate significant differences between means (P) of probands (two-way ANOVA, Tukey’s test, p < 0.001); ²Mean (I) designates the mean AUC of all twelve probands per intervention displayed per column. There were no significant differences between means (I) (two-way ANOVA, Tukey’s test, p = 0.059), which is why all values are marked with the same superscript capital letter

ISSN: 2045-7022